Search results (40)
« Back to NewsNew screening method finds novel approaches to combat antimicrobial resistant bacteria
7 May 2025
Scientists from the IOI have developed a new screening method to tackle bacterial resistance to the tetracycline class of antibiotics – providing a starting point for the development new drugs to treat drug-resistant infections.
IOI awards £5m to Oxford consortium to develop new therapies for drug-resistant tuberculosis
26 February 2025
The IOI has awarded £5 million to a group of 17 interdisciplinary researchers from the University to develop new therapies for drug-resistant tuberculosis.
IOI awarded £1m from PACE to develop a new antibiotic
21 February 2025
The Ineos Oxford Institute for antimicrobial research (IOI) has been awarded £1 million from Pathways to Antimicrobial Clinical Efficacy (PACE) to develop a new class of antibiotics based on a β-lactam-free small molecule transpeptidase inhibitor.
Sir Jim Ratcliffe awarded the University's Sheldon Medal
7 February 2025
Sir Jim Ratcliffe, Chairman of INEOS, has been presented with the Sheldon Medal by the University of Oxford in recognition of the company’s exceptionally generous support for research into antimicrobial resistance.
In The Conversation: Why is it so difficult to make a new antibiotic?
25 November 2024
Following the development of penicillin in the mid-1940s, many new classes of antibiotics were developed. Over the past 40 years however, very few have been approved. The Ineos Oxford Institute looks at why is it so difficult to make a new antibiotic.
In The Conversation: We studied drug-resistant bacteria on hospital surfaces in six countries. This is what we found.
21 November 2024
Ineos Oxford Institute for Antimicrobial Research carried out a study to investigate antimicrobial resistance-carrying bacteria recovered from surfaces in ten hospitals from six low- and middle-income countries.
New research network unites global fight against antimicrobial resistance
9 October 2024
A new University-wide network on antimicrobial resistance aims to generate novel research and collaborations to tackle one of the most urgent global health threats. The new Oxford AMR Network will unite researchers across the life sciences, medical and social sciences, and humanities.
Expert Comment: Three key pillars to tackle antimicrobial resistance effectively
26 September 2024
Timothy Walsh, Director of Biology at the Ineos Oxford Institute for antimicrobial research outlines three priorities that global leaders must consider at the UN High-Level Meeting on AMR held on 26 September.
In The Conversation: Babies in Nigeria are being born with antibiotic resistant bacteria
5 August 2024
Samples taken from mothers and newborn babies younger than one week in Nigeria already had colistin-resistant bacteria present in their bodies. But neither the babies nor their mothers had been treated with colistin.
The Oxford students at the forefront of the fight against microbial resistance
30 July 2024
At the Ineos Oxford Institute for antimicrobial research (IOI), created in 2021 to advance antimicrobial research, Oxford’s graduate students are among those contributing to the search for solutions to tackle this growing threat to global health.
New study shows tiny animals steal antibiotic recipes from bacteria
19 July 2024
A group of small freshwater animals protect themselves from infections using antibiotic recipes stolen from bacteria, according to new research led by the University of Oxford that could help develop future medicines.
In The Conversation: Tiny animals use stolen genes to fight infections – and could fight antibiotic resistance too
18 July 2024
A little-known group of microscopic animals has spent millions of years copying recipes for antibiotics from bacteria and using them to fight infections. Could this unusual defensive strategy could offer short-cuts in the race to develop antimicrobial treatments?
New molecule found to suppress bacterial antibiotic resistance evolution
29 May 2024
A new study led by researchers at the Ineos Oxford Institute for antimicrobial research (IOI) and the Department of Pharmacology offers hope in the discovery of a small molecule that works alongside antibiotics to suppress the evolution of drug-resistance in bacteria.
Novel triple drug combination effective against antibiotic-resistant bacteria
3 May 2024
Scientists at the Ineos Oxford Institute (IOI) have found a new potential combination therapy to combat antimicrobial resistance (AMR) by targeting two key bacterial enzymes involved in resistance. The findings have been published in the journal Engineering.
Colistin resistant bacteria found in mothers and newborn babies in Nigeria
27 March 2024
Researchers from the Ineos Oxford Institute for antimicrobial research (IOI) and Cardiff University have found evidence that bacteria resistant to colistin, a last-resort antibiotic, were present in mothers and babies under a week old in Nigeria in 2016, despite limited clinical use of colistin at that time in the country.
Transformative solutions to antibiotic resistance
5 March 2024
Researchers at the Department of Engineering Science are the only non-US partner in the DARTS project, which will combine the power of artificial intelligence, high-throughput testing and robotics to develop a step-change technology to diagnose antibiotic resistance.
Sir Stewart Cole joins the Ineos Oxford Institute for antimicrobial research as Executive Chair
9 January 2024
Sir Stewart Cole, KCMG, FRS has joined the Ineos Oxford Institute for antimicrobial research (IOI) as Executive Chair. The IOI is a world-leading centre of research, training and education in the field of antimicrobial resistance (AMR) based at the University of Oxford.
Antibiotic resistance genes are spread more widely between bacteria than previously thought
7 December 2023
Researchers at the Ineos Oxford Institute for antimicrobial research (IOI) at Oxford University and Fujian Agriculture and Forestry University in China have developed a new approach to study the transmission of plasmids containing antibiotic resistance genes between bacteria sampled from hospital wastewater.
Armed to the hilt: Study solves mystery behind bacteria’s extensive weaponry
5 December 2023
A new study led by the University of Oxford has shed light on why certain species of bacteria carry astonishing arsenals of weapons. The new findings could help us to engineer microbes that can destroy deadly pathogens, reducing our reliance on antibiotics.